Simbec-Orion (Pol)sp. z o.o.

Former Nurse Declared Cancer-Free after pioneering HIPEC treatment

A patient's HIPEC recovery highlights growing evidence for the treatment and what it means for oncology clinical trial development.

Personalised mRNA Vaccine Shows Promise in Preventing Melanoma Return

Melanoma is one of the more aggressive forms of skin cancer, and patients with high-risk disease remain at risk of recurrence even after successful surgery. New results from a phase III trial suggest that may be about to change for some patients. Merck (known as MSD outside the US) and Moderna have announced that a […]

What the Bundibugyo Ebola Vaccine Trial Teaches Us About Rapid Vaccine Trial Delivery

A newly launched Phase I trial from the University of Oxford illustrates how rapid vaccine trial delivery can move at speed while meeting the same regulatory and safety standards, with clear relevance to outbreak response. The trial, conducted in Oxford, will assess the safety and immune response of the ChAdOx1 BDBV vaccine candidate in 50 […]

Efficacy Endpoints in Oncology Clinical Trials: How Researchers Measure Treatment Success

Cancer drug development has evolved rapidly over the past decade. Advances in immunotherapy, precision medicine, cell therapies, and targeted treatments have created new opportunities for improving patient outcomes, but they have also increased the complexity of clinical development. Demonstrating whether a treatment delivers meaningful clinical benefit is a fundamental part of oncology research and drug […]

New Clinical Trial shows millions of breast cancer patients could avoid chemotherapy

2 million people worldwide are diagnosed with breast cancer each year. As the world’s most prevalent form of the disease, treatment has previously focused on rounds of chemotherapy to shrink the tumours. While in many cases chemotherapy has been found to be highly effective at eliminating cancer cells and reducing the risk of recurrence, its […]

Real-World Evidence in Clinical Trials: RWE vs RCTs in Modern Drug Development

Clinical research is evolving rapidly. While randomised controlled trials (RCTs) remain the gold standard for establishing the safety and efficacy of new therapies, there is increasing recognition that understanding how treatments perform in real-world clinical settings is equally important. This shift has accelerated the use of real-world evidence (RWE) in drug development. Regulatory bodies, including […]